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human DSTN shRNA silencing AAV

Name 
AAV-h-DSTN-shRNA
Cat No 
shAAV-207359
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DSTN.

shAAV-207359
AAV-h-DSTN-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DSTN (destrin, actin depolymerizing factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACTDP; ADF; bA462D18.2; HEL32
Description (Vector)
The product of this gene belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin). Two transcript variants encoding distinct isoforms have been identified for this gene.
Gene ID
11034
Gene Name (Vector)
destrin, actin depolymerizing factor
Gene Symbol
DSTN
HGNC ID
HGNC:15750
ORF Size (aa)
498
RefSeq ID
NM_006870
RefSeq Synonyms
NM_006870, NM_001011546, BC009477,
Species
human
UniGene ID
Hs.705996

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.