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human DPYS shRNA silencing AAV

Name 
AAV-h-DPYS-shRNA
Cat No 
shAAV-207309
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DPYS.

shAAV-207309
AAV-h-DPYS-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DPYS (dihydropyrimidinase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DHP; DHPase
Description (Vector)
Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Gene ID
1807
Gene Name (Vector)
dihydropyrimidinase
Gene Symbol
DPYS
HGNC ID
HGNC:3013
ORF Size (aa)
1560
ORF Size (bp)
1560 bp
RefSeq ID
NM_001385
RefSeq Synonyms
NM_001385, BC034395,
Species
human
UniGene ID
Hs.443161

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.