human DPH2 shRNA silencing AAV

Name 
AAV-h-DPH2-shRNA
Cat No 
shAAV-207274
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DPH2.

shAAV-207274
AAV-h-DPH2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DPH2 (DPH2 homolog). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DPH2L2
Description (Vector)
DPH2 is one of two human genes similar to the yeast gene dph2. The yeast gene was identified by its ability to complement a diphthamide mutant strain, and thus probably functions in diphthamide biosynthesis. Diphthamide is a post-translationally modified histidine residue present in elongation factor 2 (EF2) that is the target of diphtheria toxin ADP-ribosylation. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1802
Gene Name (Vector)
DPH2 homolog
Gene Symbol
DPH2
HGNC ID
HGNC:3004
ORF Size (aa)
1470
ORF Size (bp)
1470 bp
RefSeq ID
NM_001384
RefSeq Synonyms
NM_001384, NM_001319171, NM_001319170, NM_001319169, NM_001319168, NM_001319167, NM_001319166, NM_001319165, NM_001039589, BC016956, BC003181, BC001389,
Species
human
UniGene ID
Hs.632398

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.