human DOC2A shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DOC2A.
shAAV-207218
AAV-h-DOC2A-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DOC2A (double C2 domain alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Doc2
Description (Vector)
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Gene ID
8448
Gene Name (Vector)
double C2 domain alpha
Gene Symbol
DOC2A
HGNC ID
HGNC:2985
ORF Size (aa)
1203
RefSeq ID
NM_003586
RefSeq Synonyms
NM_003586, NM_001282068, NM_001282063, NM_001282062, BC063436, BC055284, BC041769,
Species
human
UniGene ID
Hs.355281
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.