human DND1 shRNA silencing AAV

Name 
AAV-h-DND1-shRNA
Cat No 
shAAV-207196
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DND1.

shAAV-207196
AAV-h-DND1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DND1 (DND microRNA-mediated repression inhibitor 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RBMS4
Description (Vector)
DND1 encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.
Gene ID
373863
Gene Name (Vector)
DND microRNA-mediated repression inhibitor 1
Gene Symbol
DND1
HGNC ID
HGNC:23799
ORF Size (aa)
1062
ORF Size (bp)
1062 bp
RefSeq ID
NM_194249
RefSeq Synonyms
NM_194249, BC033496,
Species
human
UniGene ID
Hs.591262

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.