human DNASE1L3 shRNA silencing AAV

Name 
AAV-h-DNASE1L3-shRNA
Cat No 
shAAV-207191
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DNASE1L3.

shAAV-207191
AAV-h-DNASE1L3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNASE1L3 (deoxyribonuclease 1 like 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DHP2; DNAS1L3; LSD; SLEB16
Description (Vector)
DNASE1L3 encodes a member of the deoxyribonuclease I family. The encoded protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Mutations in this gene are a cause of systemic lupus erythematosus-16. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
1776
Gene Name (Vector)
deoxyribonuclease 1 like 3
Gene Symbol
DNASE1L3
HGNC ID
HGNC:2959
ORF Size (aa)
918
ORF Size (bp)
918 bp
RefSeq ID
NM_004944
RefSeq Synonyms
NM_004944, NM_001256560, BC015831,
Species
human
UniGene ID
Hs.476453

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.