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human DNAJC9 shRNA silencing AAV

Name 
AAV-h-DNAJC9-shRNA
Cat No 
shAAV-207181
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DNAJC9.

shAAV-207181
AAV-h-DNAJC9-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAJC9 (DnaJ heat shock protein family (Hsp40) member C9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DnaJ (Hsp40) homolog, subfamily C, member 9; dnaJ homolog subfamily C member 9; DnaJ protein SB73; HDJC9; JDD1; SB73
Description (eCommerce)
DjC9 (DnaJ subfamily C member 9) belongs to the Hsp40 (heat shock protein 40) family of proteins that function as co-chaperones to Hsp70.Hsp40 proteins are classified into 3 main subfamilies (A, B, and C). The families are defined by the presence of particular domains which include a highly conserved alpha-helical N-terminal domain termed the J-domain, a glycine/phenylalanine-rich region, a cysteine-rich region, and a C-terminal beta-sheet containing domain. DjC9 is part of subfamily C that bears only the J-domain. DjC9 has been shown to interact with HSP70 through its J domain and activate its ATPase activity.
Gene ID
23234
Gene Name (eCommerce)
DnaJ heat shock protein family (Hsp40) member C9
Gene Name (Vector)
DnaJ heat shock protein family (Hsp40) member C9
Gene Symbol
DNAJC9
HGNC ID
HGNC:19123
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
783
ORF Size (bp)
783 bp
Protein Name (eCommerce)
DnaJ homolog subfamily C member 9
RefSeq ID
NM_015190
RefSeq Synonyms
NM_015190, BC136507,
Research Areas
Neurobiology,Protein Folding,Transcription Factor/Regulator,Transport
Research Areas (Faceted)
cell_biology,neurobiology,transcription_translation
Species
human
Target Sentence
DjC9 (DnaJ subfamily C member 9) belongs to the Hsp40 (heat shock protein 40) family of proteins that function as co-chaperones to Hsp70.Hsp40 proteins are classified into 3 main subfamilies (A, B, and C). The families are defined by the presence of particular domains which include a highly conserved alpha-helical N-terminal domain termed the J-domain, a glycine/phenylalanine-rich region, a cysteine-rich region, and a C-terminal beta-sheet containing domain. DjC9 is part of subfamily C that bears only the J-domain. DjC9 has been shown to interact with HSP70 through its J domain and activate its ATPase activity.
UniGene ID
Hs.654694
UniProt ID (eCommerce)
Q8WXX5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.