human DNAJC8 shRNA silencing AAV

Name
AAV-h-DNAJC8-shRNA

Cat No
shAAV-207180

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human DNAJC8.

shAAV-207180

AAV-h-DNAJC8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DnaJ (Hsp40) homolog, subfamily C, member 8; dnaJ homolog subfamily C member 8; HSPC331; SPF31; splicing protein spf31

Description (eCommerce)

DjC8 (DnaJ subfamily C member 8) belongs to the Hsp40 (heat shock protein 40) family of proteins that function as co-chaperones to Hsp70.Hsp40 proteins are classified into 3 main subfamilies (A, B, and C). The families are defined by the presence of particular domains which include a highly conserved alpha-helical N-terminal domain termed the J-domain, a glycine/phenylalanine-rich region, a cysteine-rich region, and a C-terminal beta-sheet containing domain. Djc8 is part of subfamily C that bears only the J-domain.

Gene ID

22826

Gene Name (eCommerce)

DnaJ heat shock protein family (Hsp40) member C8

Gene Name (Vector)

DnaJ heat shock protein family (Hsp40) member C8

Gene Symbol

DNAJC8

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

762

ORF Size (bp)

762 bp

Protein Name (eCommerce)

DnaJ homolog subfamily C member 8

RefSeq ID

NM_014280

RefSeq Synonyms

NM_014280, BC033159,

Research Areas

Gene Expression,mRNA Processing,mRNA Splicing,Protein Folding,RNA Processing,Spliceosome,Transcription Factor/Regulator,Transport

Research Areas (Faceted)

genetics,transcription_translation,cell_biology

Species

human

Target Sentence

DjC8 (DnaJ subfamily C member 8) belongs to the Hsp40 (heat shock protein 40) family of proteins that function as co-chaperones to Hsp70.Hsp40 proteins are classified into 3 main subfamilies (A, B, and C). The families are defined by the presence of particular domains which include a highly conserved alpha-helical N-terminal domain termed the J-domain, a glycine/phenylalanine-rich region, a cysteine-rich region, and a C-terminal beta-sheet containing domain. Djc8 is part of subfamily C that bears only the J-domain.

UniGene ID

Hs.433540

UniProt ID (eCommerce)

O75937

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.