human DNAJB2 shRNA silencing AAV

Name
AAV-h-DNAJB2-shRNA

Cat No
shAAV-207133

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DNAJB2.

shAAV-207133

AAV-h-DNAJB2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CMT2T; DSMA5; HSJ-1; HSJ1; HSPF3

Description (Vector)

DNAJB2 is almost exclusively expressed in the brain, mainly in the neuronal layers. It encodes a protein that shows sequence similarity to bacterial DnaJ protein and the yeast homologs. In bacteria, this protein is implicated in protein folding and protein complex dissociation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene ID

3300

Gene Name (Vector)

DnaJ heat shock protein family (Hsp40) member B2

Gene Symbol

DNAJB2

HGNC ID

HGNC:5228

ORF Size (aa)

975

ORF Size (bp)

975 bp

RefSeq ID

NM_006736

RefSeq Synonyms

NM_006736, NM_001039550, BC047056, BC011609,

Species

human

UniGene ID

Hs.77768

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.