human DNA2 shRNA silencing AAV

Name 
AAV-h-DNA2-shRNA
Cat No 
shAAV-207113
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DNA2.

shAAV-207113
AAV-h-DNA2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DNA2 (DNA replication helicase/nuclease 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DNA2L; hDNA2
Description (Vector)
DNA2 is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability (Duxin et al., 2009 (PubMed 19487465)).(supplied by OMIM, Nov 2010)
Gene ID
1763
Gene Name (Vector)
DNA replication helicase/nuclease 2
Gene Symbol
DNA2
HGNC ID
HGNC:2939
ORF Size (aa)
2064
ORF Size (bp)
2064 bp
RefSeq ID
NM_001080449
RefSeq Synonyms
NM_001080449, BC111740,
Species
human
UniGene ID
Hs.532446

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.