human DMXL1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DMXL1.
shAAV-207109
AAV-h-DMXL1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DMXL1 (Dmx like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
dmX-like protein 1; X-like 1 protein
Description (eCommerce)
DMXL1 is a member of the WD repeat superfamily of proteins, which have regulatory functions. It is expressed in many tissue types including several types of eye tissue, and it has been associated with ocular phenotypes. In addition, it is upregulated in cultured cells that overexpress growth factor independence 1B, a transcription factor that is essential for hematopoietic cell developmen [taken from NCBI Entrez Gene (Gene ID: 1657)].
Description (Vector)
DMXL1 is a member of a superfamily of WD repeat proteins. The function of this protein is not yet determined; however, other related family members perform functions involved in regulatory processes.
Gene ID
1657
Gene Name (eCommerce)
Dmx like 1
Gene Name (Vector)
Dmx like 1
Gene Symbol
DMXL1
HGNC ID
HGNC:2937
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
9147
ORF Size (bp)
9147 bp
Protein Name (eCommerce)
DmX-like protein 1
RefSeq ID
NM_005509
RefSeq Synonyms
NM_005509, NM_001290322, NM_001290321, BC150616, BC144537,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
DMXL1 is a member of the WD repeat superfamily of proteins, which have regulatory functions. It is expressed in many tissue types including several types of eye tissue, and it has been associated with ocular phenotypes. In addition, it is upregulated in cultured cells that overexpress growth factor independence 1B, a transcription factor that is essential for hematopoietic cell developmen [taken from NCBI Entrez Gene (Gene ID: 1657)].
UniGene ID
Hs.181042
UniProt ID (eCommerce)
Q9Y485
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.