human DMRT2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DMRT2.
shAAV-207096
AAV-h-DMRT2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DMRT2 (doublesex and mab-3 related transcription factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
DMRT2 belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9.
Gene ID
10655
Gene Name (Vector)
doublesex and mab-3 related transcription factor 2
Gene Symbol
DMRT2
HGNC ID
HGNC:2935
ORF Size (aa)
1686
ORF Size (bp)
1686 bp
RefSeq ID
NM_006557
RefSeq Synonyms
NM_181872, NM_006557, NM_001130865, BC136493,
Species
human
UniGene ID
Hs.59506
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.