human DLL3 shRNA silencing AAV

Name
AAV-h-DLL3-shRNA

Cat No
shAAV-207061

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DLL3.

shAAV-207061

AAV-h-DLL3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DLL3 (delta like canonical Notch ligand 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

SCDO1

Description (Vector)

DLL3 encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene ID

10683

Gene Name (Vector)

delta like canonical Notch ligand 3

Gene Symbol

DLL3

HGNC ID

HGNC:2909

ORF Size (aa)

1857

ORF Size (bp)

1857 bp

RefSeq ID

NM_016941

RefSeq Synonyms

NM_203486, NM_016941, BC000218,

Species

human

UniGene ID

Hs.127792

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.