human DKK3 shRNA silencing AAV

Name
AAV-h-DKK3-shRNA

Cat No
shAAV-207028

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human DKK3.

shAAV-207028

AAV-h-DKK3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DKK3 (dickkopf WNT signaling pathway inhibitor 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

REIC; RIG

Description (Vector)

DKK3 encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.

Gene ID

27122

Gene Name (Vector)

dickkopf WNT signaling pathway inhibitor 3

Gene Symbol

DKK3

HGNC ID

HGNC:2893

ORF Size (aa)

1053

ORF Size (bp)

1053 bp

RefSeq ID

NM_015881

RefSeq Synonyms

NM_015881, NM_013253, NM_001330220, NM_001018057, BC007660,

Species

human

UniGene ID

Hs.292156

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.