human DIAPH3 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DIAPH3.
shAAV-206987
AAV-h-DIAPH3-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DIAPH3 (diaphanous related formin 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AN; AUNA1; DIA2; diap3; diaphanous homolog 3; Diaphanous-related formin-3; DRF3; mDia2; NSDAN; protein diaphanous homolog 3
Description (eCommerce)
DIAPH3 encodes for protein diaphanous homolog 3, a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in DIAPH3 are associated with autosomal dominant auditory neuropathy 1 [taken from NCBI Entrez Gene (Gene ID: 81624)].
Description (Vector)
DIAPH3 encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
81624
Gene Name (eCommerce)
diaphanous related formin 3
Gene Name (Vector)
diaphanous related formin 3
Gene Symbol
DIAPH3
HGNC ID
HGNC:15480
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2550
ORF Size (bp)
2550 bp
Protein Name (eCommerce)
Protein diaphanous homolog 3
RefSeq ID
NM_030932
RefSeq Synonyms
NM_030932, NM_001258370, NM_001258369, NM_001258368, NM_001258367, NM_001258366, NM_001042517, BC068504, BC048963, BC034952,
Research Areas
Cytoskeleton,Neurobiology,Neurodevelopment
Research Areas (Faceted)
cell_biology,neurobiology,developmental_biology
Species
human
Target Sentence
DIAPH3 encodes for protein diaphanous homolog 3, a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in DIAPH3 are associated with autosomal dominant auditory neuropathy 1 [taken from NCBI Entrez Gene (Gene ID: 81624)].
UniGene ID
Hs.283127
UniProt ID (eCommerce)
Q9NSV4
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.