human DGCR6 shRNA silencing AAV

Name 
AAV-h-DGCR6-shRNA
Cat No 
shAAV-206914
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DGCR6.

shAAV-206914
AAV-h-DGCR6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DGCR6 (DiGeorge syndrome critical region gene 6). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia.
Gene ID
8214
Gene Name (Vector)
DiGeorge syndrome critical region gene 6
Gene Symbol
DGCR6
HGNC ID
HGNC:2846
ORF Size (aa)
663
ORF Size (bp)
663 bp
RefSeq ID
NM_005675
RefSeq Synonyms
NM_005675, BC047039,
Species
human
UniGene ID
Hs.474185

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.