human DGCR2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DGCR2.
shAAV-206911
AAV-h-DGCR2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DGCR2 (DiGeorge syndrome critical region gene 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DGS-C; IDD; LAN; SEZ-12
Description (Vector)
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Alternative splicing results in multiple transcript variants.
Gene ID
9993
Gene Name (Vector)
DiGeorge syndrome critical region gene 2
Gene Symbol
DGCR2
HGNC ID
HGNC:2845
ORF Size (aa)
1653
ORF Size (bp)
1653 bp
RefSeq ID
NM_005137
RefSeq Synonyms
NM_005137, NM_001184781, NM_001173534, NM_001173533, BC040500, BC032430,
Species
human
UniGene ID
Hs.517357
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.