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human DFNB59 shRNA silencing AAV

Name 
AAV-h-DFNB59-shRNA
Cat No 
shAAV-206904
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DFNB59.

shAAV-206904
AAV-h-DFNB59-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DFNB59 (deafness, autosomal recessive 59). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PJVK
Description (Vector)
DFNB59 is a member of the gasdermin family, a family which is found only in vertebrates. The encoded protein is required for the proper function of auditory pathway neurons. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal recessive type 59 (DFNB59).
Gene ID
494513
Gene Name (Vector)
deafness, autosomal recessive 59
Gene Symbol
DFNB59
HGNC ID
HGNC:29502
ORF Size (aa)
582
ORF Size (bp)
582 bp
RefSeq ID
NM_001042702
RefSeq Synonyms
NM_001042702, BC146938, BC127903, BC127902,
Species
human
UniGene ID
Hs.87734

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.