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human DFNA5 shRNA silencing AAV

Name 
AAV-h-DFNA5-shRNA
Cat No 
shAAV-206898
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DFNA5.

shAAV-206898
AAV-h-DFNA5-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DFNA5 (DFNA5, deafness associated tumor suppressor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ICERE-1
Description (Vector)
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.
Gene ID
1687
Gene Name (Vector)
DFNA5, deafness associated tumor suppressor
Gene Symbol
DFNA5
HGNC ID
HGNC:2810
ORF Size (aa)
1491
ORF Size (bp)
1491 bp
RefSeq ID
NM_004403
RefSeq Synonyms
NM_004403, NM_001127454, NM_001127453, BC125065, BC099911, BC019689,
Species
human
UniGene ID
Hs.520708

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.