human DERL2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DERL2.
shAAV-206887
AAV-h-DERL2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DERL2 (derlin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CGI-101; derlin-2; DERtrin-2; F-LAN-1; F-LANa; FLANa
Description (Vector)
Proteins that are unfolded or misfolded in the endoplasmic reticulum (ER) must be refolded or degraded to maintain the homeostasis of the ER. DERL2 is involved in the degradation of misfolded glycoproteins in the ER (Oda et al., 2006 (PubMed 16449189)).(supplied by OMIM, Mar 2008)
Gene ID
51009
Gene Name (Vector)
derlin 2
Gene Symbol
DERL2
HGNC ID
HGNC:17943
ORF Size (aa)
720
RefSeq ID
NM_016041
RefSeq Synonyms
NM_016041, NM_001304779, NM_001304777, BC010890,
Species
human
UniGene ID
Hs.286131
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.