human DEGS2 shRNA silencing AAV

Name 
AAV-h-DEGS2-shRNA
Cat No 
shAAV-206861
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DEGS2.

shAAV-206861
AAV-h-DEGS2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DEGS2 (delta 4-desaturase, sphingolipid 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C14orf66; DES2; FADS8
Description (Vector)
DEGS2 encodes a bifunctional enzyme that is involved in the biosynthesis of phytosphingolipids in human skin and in other phytosphingolipid-containing tissues. This enzyme can act as a sphingolipid delta(4)-desaturase, and also as a sphingolipid C4-hydroxylase.
Gene ID
123099
Gene Name (Vector)
delta 4-desaturase, sphingolipid 2
Gene Symbol
DEGS2
HGNC ID
HGNC:20113
ORF Size (aa)
972
ORF Size (bp)
972 bp
RefSeq ID
NM_206918
RefSeq Synonyms
NM_206918, BC063598,
Species
human
UniGene ID
Hs.159643

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.