human DEF6 shRNA silencing AAV

Name
AAV-h-DEF6-shRNA

Cat No
shAAV-206789

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human DEF6.

shAAV-206789

AAV-h-DEF6-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DEF6 (DEF6, guanine nucleotide exchange factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

IBP; SLAT; SWAP70L

Description (Vector)

DEF6, or IBP, is a guanine nucleotide exchange factor (GEF) for RAC (MIM 602048) and CDC42 (MIM 116952) that is highly expressed in B and T cells (Gupta et al., 2003 (PubMed 12923183)).(supplied by OMIM, Mar 2008)

Gene ID

50619

Gene Name (Vector)

DEF6, guanine nucleotide exchange factor

Gene Symbol

DEF6

HGNC ID

HGNC:2760

ORF Size (aa)

1896

ORF Size (bp)

1896 bp

RefSeq ID

NM_022047

RefSeq Synonyms

NM_022047, BC168373, BC017504,

Species

human

UniGene ID

Hs.15476

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.