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human DEDD2 shRNA silencing AAV

Name 
AAV-h-DEDD2-shRNA
Cat No 
shAAV-206788
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DEDD2.

shAAV-206788
AAV-h-DEDD2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DEDD2 (death effector domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
FLAME-3; FLAME3
Description (Vector)
DEDD2 encodes a nuclear-localized protein containing a death effector domain (DED). The encoded protein may regulate the trafficking of caspases and other proteins into the nucleus during death receptor-induced apoptosis. Alternative splicing results in multiple transcript variants.
Gene ID
162989
Gene Name (Vector)
death effector domain containing 2
Gene Symbol
DEDD2
HGNC ID
HGNC:24450
ORF Size (aa)
981
ORF Size (bp)
981 bp
RefSeq ID
NM_133328
RefSeq Synonyms
NM_133328, NM_001270615, NM_001270614, BC027930, BC013372,
Species
human
UniGene ID
Hs.515432

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.