human DDX58 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DDX58.
shAAV-206774
AAV-h-DDX58-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DDX58 (DExD/H-box helicase 58). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
RIG-I; RIGI; RLR-1; SGMRT2
Description (Vector)
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response.
Gene ID
23586
Gene Name (Vector)
DExD/H-box helicase 58
Gene Symbol
DDX58
HGNC ID
HGNC:19102
ORF Size (aa)
2778
ORF Size (bp)
2778 bp
RefSeq ID
NM_014314
RefSeq Synonyms
NM_014314, BC136610, BC132786,
Species
human
UniGene ID
Hs.190622
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.