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human DCTPP1 shRNA silencing AAV

Name 
AAV-h-DCTPP1-shRNA
Cat No 
shAAV-206682
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human DCTPP1.

shAAV-206682
AAV-h-DCTPP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DCTPP1 (dCTP pyrophosphatase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CDA03; dCTP pyrophosphatase 1; dCTPase 1; deoxycytidine-triphosphatase 1; RS21C6; XTP3TPA; XTP3-transactivated gene A protein; XTP3-transactivated protein A
Description (eCommerce)
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H773].
Gene ID
79077
Gene Name (eCommerce)
dCTP pyrophosphatase 1
Gene Name (Vector)
dCTP pyrophosphatase 1
Gene Symbol
DCTPP1
HGNC ID
HGNC:28777
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
513
ORF Size (bp)
513 bp
Protein Name (eCommerce)
dCTP pyrophosphatase 1
RefSeq ID
NM_024096
RefSeq Synonyms
NM_024096, BC001344,
Research Areas
Cell Biology,Metabolism/Metabolic Process,Phosphatase
Research Areas (Faceted)
cell_biology,metabolism
Species
human
Target Sentence
DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H773].
UniGene ID
Hs.632191
UniProt ID (eCommerce)
Q9H773

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.