human DCP1B shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DCP1B.
shAAV-206664
AAV-h-DCP1B-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DCP1B (decapping mRNA 1B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
DCP1; DCP1 decapping enzyme homolog B; decapping enzyme hDcp1b; mRNA-decapping enzyme 1B
Description (eCommerce)
mRNA-decapping enzyme 1B (DCP1B) may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IZD4].
Description (Vector)
DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 (PubMed 12417715)).(supplied by OMIM, Mar 2008)
Gene ID
196513
Gene Name (eCommerce)
decapping mRNA 1B
Gene Name (Vector)
decapping mRNA 1B
Gene Symbol
DCP1B
HGNC ID
HGNC:24451
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1857
ORF Size (bp)
1857 bp
Protein Name (eCommerce)
mRNA-decapping enzyme 1B
RefSeq ID
NM_152640
RefSeq Synonyms
NM_152640, NM_001319292, BC043437,
Research Areas
Gene Expression,RNA Processing
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
mRNA-decapping enzyme 1B (DCP1B) may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (by similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q8IZD4].
UniGene ID
Hs.130934
UniProt ID (eCommerce)
Q8IZD4
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.