human DBH shRNA silencing AAV

Name
AAV-h-DBH-shRNA

Cat No
shAAV-206620

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human DBH.

shAAV-206620

AAV-h-DBH-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DBH (dopamine beta-hydroxylase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DBM

Description (Vector)

DBH is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.

Gene ID

1621

Gene Name (Vector)

dopamine beta-hydroxylase

Gene Symbol

DBH

HGNC ID

HGNC:2689

ORF Size (aa)

1812

ORF Size (bp)

1812 bp

RefSeq ID

NM_000787

RefSeq Synonyms

NM_000787, BC017174,

Species

human

UniGene ID

Hs.591890

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.