human DAZAP2 shRNA silencing AAV

Name
AAV-h-DAZAP2-shRNA

Cat No
shAAV-206612

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human DAZAP2.

shAAV-206612

AAV-h-DAZAP2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human DAZAP2 (DAZ associated protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

PRTB

Description (Vector)

DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

9802

Gene Name (Vector)

DAZ associated protein 2

Gene Symbol

DAZAP2

HGNC ID

HGNC:2684

ORF Size (aa)

507

ORF Size (bp)

507 bp

RefSeq ID

NM_014764

RefSeq Synonyms

NM_014764, NM_001136269, NM_001136268, NM_001136267, NM_001136266, NM_001136264, BC007900, BC002334,

Species

human

UniGene ID

Hs.369761

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.