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human CYGB shRNA silencing AAV

Name 
AAV-h-CYGB-shRNA
Cat No 
shAAV-206435
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CYGB.

shAAV-206435
AAV-h-CYGB-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CYGB (cytoglobin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HGB; STAP
Description (Vector)
CYGB encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. CYGB is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.
Gene ID
114757
Gene Name (Vector)
cytoglobin
Gene Symbol
CYGB
HGNC ID
HGNC:16505
ORF Size (aa)
573
ORF Size (bp)
573 bp
RefSeq ID
NM_134268
RefSeq Synonyms
NM_134268, BC029798,
Species
human
UniGene ID
Hs.95120

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.