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human CYBA shRNA silencing AAV

Name 
AAV-h-CYBA-shRNA
Cat No 
shAAV-206404
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CYBA.

shAAV-206404
AAV-h-CYBA-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CYBA (cytochrome b-245 alpha chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
p22-PHOX
Description (Vector)
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
Gene ID
1535
Gene Name (Vector)
cytochrome b-245 alpha chain
Gene Symbol
CYBA
HGNC ID
HGNC:2577
ORF Size (aa)
588
ORF Size (bp)
588 bp
RefSeq ID
NM_000101
RefSeq Synonyms
NM_000101, BC028224, BC006465,
Species
human
UniGene ID
Hs.513803

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.