human CXCL13 shRNA silencing AAV

Name
AAV-h-CXCL13-shRNA

Cat No
shAAV-206332

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human CXCL13.

shAAV-206332

AAV-h-CXCL13-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CXCL13 (C-X-C motif chemokine ligand 13). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

ANGIE; ANGIE2; BCA-1; BCA1; BLC; BLR1L; SCYB13

Description (Vector)

B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles.

Gene ID

10563

Gene Name (Vector)

C-X-C motif chemokine ligand 13

Gene Symbol

CXCL13

HGNC ID

HGNC:10639

ORF Size (aa)

330

ORF Size (bp)

330 bp

RefSeq ID

NM_006419

RefSeq Synonyms

NM_006419, BC012589,

Species

human

UniGene ID

Hs.100431

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.