human CRLF2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CRLF2.
shAAV-206025
AAV-h-CRLF2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CRLF2 (cytokine receptor-like factor 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CRL2; CRLF2Y; TSLPR
Description (Vector)
CRLF2 is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
64109
Gene Name (Vector)
cytokine receptor-like factor 2
Gene Symbol
CRLF2
HGNC ID
HGNC:14281
ORF Size (aa)
1116
ORF Size (bp)
1116 bp
RefSeq ID
NM_022148
RefSeq Synonyms
NM_022148, NM_001012288, BC160055,
Species
human
UniGene ID
Hs.287729
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.