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human CRAT shRNA silencing AAV

Name 
AAV-h-CRAT-shRNA
Cat No 
shAAV-205962
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CRAT.

shAAV-205962
AAV-h-CRAT-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CRAT (carnitine O-acetyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CAT; CAT1
Description (Vector)
CRAT encodes carnitine acetyltransferase (CRAT), which is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Two transcript variants encoding different isoforms have been found for this gene.
Gene ID
1384
Gene Name (Vector)
carnitine O-acetyltransferase
Gene Symbol
CRAT
HGNC ID
HGNC:2342
ORF Size (aa)
1635
ORF Size (bp)
1635 bp
RefSeq ID
NM_000755
RefSeq Synonyms
NM_004003, NM_001346549, NM_001346548, NM_001346547, NM_001346546, NM_001257363, NM_000755, BC000723,
Species
human
UniGene ID
Hs.12068

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.