human CRADD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CRADD.
shAAV-205957
AAV-h-CRADD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CRADD (CASP2 and RIPK1 domain containing adaptor with death domain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MRT34; RAIDD
Description (Vector)
CRADD is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
Gene ID
8738
Gene Name (Vector)
CASP2 and RIPK1 domain containing adaptor with death domain
Gene Symbol
CRADD
HGNC ID
HGNC:2340
ORF Size (aa)
600
ORF Size (bp)
600 bp
RefSeq ID
NM_003805
RefSeq Synonyms
NM_003805, NM_001330126, NM_001320101, NM_001320100, NM_001320099, BC037905, BC017042,
Species
human
UniGene ID
Hs.591016
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.