human CPSF3 shRNA silencing AAV

Name 
AAV-h-CPSF3-shRNA
Cat No 
shAAV-205926
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CPSF3.

shAAV-205926
AAV-h-CPSF3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CPSF3 (cleavage and polyadenylation specific factor 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cleavage and polyadenylation specific factor 3, 73kDa; Cleavage and polyadenylation specificity factor 73 kDa subunit; cleavage and polyadenylation specificity factor subunit 3; CPSF 73 kDa subunit; CPSF73; CPSF-73; mRNA 3'-end-processing endonuclease CPSF-73
Description (eCommerce)
CPSF73 is the 73 kDa subunit of the cleavage and polyadenylation specificity factor (CPSF) complex that functions in pre-mRNA-3’-end formation. CPSF73 has been implicated as the endonuclease component of the CPSF complex for pre-mRNA-3’ end processing.
Description (Vector)
Most eukaryotic mRNA precursors (pre-mRNAs) undergo extensive maturational processing, including cleavage and polyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunit of the cleavage and polyadenylation specificity factor (CPSF) and is the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al., 2006 (PubMed 17128255)).(supplied by OMIM, Jul 2010)
Gene ID
51692
Gene Name (eCommerce)
cleavage and polyadenylation specific factor 3
Gene Name (Vector)
cleavage and polyadenylation specific factor 3
Gene Symbol
CPSF3
HGNC ID
HGNC:2326
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2055
ORF Size (bp)
2055 bp
Protein Name (eCommerce)
Cleavage and polyadenylation specificity factor subunit 3
RefSeq ID
NM_016207
RefSeq Synonyms
NM_016207, NM_001321836, NM_001321835, NM_001321834, NM_001321833, BC020211, BC011654,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,mRNA Transport,RNA Binding,RNA Processing,RNA Transport,Spliceosome
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
CPSF73 is the 73 kDa subunit of the cleavage and polyadenylation specificity factor (CPSF) complex that functions in pre-mRNA-3’-end formation. CPSF73 has been implicated as the endonuclease component of the CPSF complex for pre-mRNA-3’ end processing.
UniGene ID
Hs.515972
UniProt ID (eCommerce)
Q9UKF6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.