human CPS1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CPS1.
shAAV-205923
AAV-h-CPS1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CPS1 (carbamoyl-phosphate synthase 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CPSASE1; PHN
Description (Vector)
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
Gene ID
1373
Gene Name (Vector)
carbamoyl-phosphate synthase 1
Gene Symbol
CPS1
HGNC ID
HGNC:2323
ORF Size (aa)
4503
ORF Size (bp)
4503 bp
RefSeq ID
NM_001875
RefSeq Synonyms
NM_001875, NM_001122634, NM_001122633, BC140943,
Species
human
UniGene ID
Hs.149252
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.