human CPD shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CPD.
shAAV-205879
AAV-h-CPD-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CPD (carboxypeptidase D). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
carboxypeptidase D; GP180; metallocarboxypeptidase D
Description (eCommerce)
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D (CPD) has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein [taken from NCBI Entrez Gene (Gene ID: 1362)].
Description (Vector)
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Gene ID
1362
Gene Name (eCommerce)
carboxypeptidase D
Gene Name (Vector)
carboxypeptidase D
Gene Symbol
CPD
HGNC ID
HGNC:2301
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
4143
ORF Size (bp)
4143 bp
Protein Name (eCommerce)
Carboxypeptidase D
RefSeq ID
NM_001304
RefSeq Synonyms
NM_001304, NM_001199775, BC051702, BC045624, BC045549,
Research Areas
Golgi Apparatus,Interleukin Signaling,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology,immunology
Species
human
Target Sentence
The metallocarboxypeptidase family of enzymes is divided into 2 subfamilies based on sequence similarities. The pancreatic carboxypeptidase-like and the regulatory B-type carboxypeptidase subfamilies. Carboxypeptidase D (CPD) has been identified as a regulatory B-type carboxypeptidase. CPD is a homolog of duck gp180, a hepatitis B virus-binding protein [taken from NCBI Entrez Gene (Gene ID: 1362)].
UniGene ID
Hs.446079
UniProt ID (eCommerce)
O75976
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.