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human COX18 shRNA silencing AAV

Name 
AAV-h-COX18-shRNA
Cat No 
shAAV-205821
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human COX18.

shAAV-205821
AAV-h-COX18-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COX18 (COX18, cytochrome c oxidase assembly factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
COX18HS
Description (Vector)
COX18 encodes a cytochrome c oxidase (COX)-assembly protein. The S. cerevisiae Cox18 protein catalyzes the insertion of the Cox2 (MTCO2; MIM 516040) C-terminal tail into the mitochondrial inner membrane, an intermediate step in the assembly of complex IV of the mitochondrial respiratory chain (Sacconi et al., 2005 (PubMed 16212937)).(supplied by OMIM, Mar 2008)
Gene ID
285521
Gene Name (Vector)
COX18, cytochrome c oxidase assembly factor
Gene Symbol
COX18
HGNC ID
HGNC:26801
ORF Size (aa)
1002
ORF Size (bp)
1002 bp
RefSeq ID
NM_173827
RefSeq Synonyms
NM_173827, NM_001300729, NM_001297733, NM_001297732, BC143642, BC101684,
Species
human
UniGene ID
Hs.356697

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.