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human CORO1A shRNA silencing AAV

Name 
AAV-h-CORO1A-shRNA
Cat No 
shAAV-205796
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CORO1A.

shAAV-205796
AAV-h-CORO1A-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CORO1A (coronin 1A). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLABP; CLIPINA; clipin-A; coronin, actin binding protein, 1A; coronin-1; coronin-1A; coronin-like protein A; coronin-like protein p57; HCORO1; IMD8; p57; TACO; tryptophan aspartate-containing coat protein
Description (eCommerce)
Coronin 1 is a conserved actin-associated protein that functions in actin rearrangements and is important for cell motility and phagocytosis.
Description (Vector)
CORO1A encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Alternative splicing results in multiple transcript variants. A related pseudogene has been defined on chromosome 16.
Gene ID
11151
Gene Name (eCommerce)
coronin 1A
Gene Name (Vector)
coronin 1A
Gene Symbol
CORO1A
HGNC ID
HGNC:2252
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1386
ORF Size (bp)
1386 bp
Protein Name (eCommerce)
Coronin-1A
RefSeq ID
NM_007074
RefSeq Synonyms
NM_007074, NM_001193333, BC126387, BC126385, BC110374,
Research Areas
Cytoskeleton,Immunology,Innate Immunity,Neurobiology,Transport
Research Areas (Faceted)
cell_biology,immunology,neurobiology
Species
human
Target Sentence
Coronin 1 is a conserved actin-associated protein that functions in actin rearrangements and is important for cell motility and phagocytosis.
UniGene ID
Hs.415067
UniProt ID (eCommerce)
P31146

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.