human COMMD3 shRNA silencing AAV

Name 
AAV-h-COMMD3-shRNA
Cat No 
shAAV-205735
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human COMMD3.

shAAV-205735
AAV-h-COMMD3-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COMMD3 (COMM domain containing 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BUP; C10orf8; COMM domain-containing protein 3; protein Bup; Protein PIL
Description (eCommerce)
COMM domain-containing protein 3 (COMMD3) contains a COMM domain which play a role protein-protein interactions. Members of the COMMD3 family have been found to bind NF-kappaB. COMMD3 may function to down-regulate activation of NF-kappaB.
Gene ID
23412
Gene Name (eCommerce)
COMM domain containing 3
Gene Name (Vector)
COMM domain containing 3
Gene Symbol
COMMD3
HGNC ID
HGNC:23332
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
588
ORF Size (bp)
588 bp
Protein Name (eCommerce)
COMM domain-containing protein 3
RefSeq ID
NM_012071
RefSeq Synonyms
NM_012071, BC022898,
Research Areas
Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
COMM domain-containing protein 3 (COMMD3) contains a COMM domain which play a role protein-protein interactions. Members of the COMMD3 family have been found to bind NF-kappaB. COMMD3 may function to down-regulate activation of NF-kappaB.
UniGene ID
Hs.534398
UniProt ID (eCommerce)
Q9UBI1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.