human COL8A2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human COL8A2.
shAAV-205719
AAV-h-COL8A2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human COL8A2 (collagen type VIII alpha 2 chain). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
FECD; FECD1; PPCD; PPCD2
Description (Vector)
COL8A2 encodes the alpha 2 chain of type VIII collagen. The protein is a major component of the basement membrane of the corneal endothelium and forms homo- or heterotrimers with alpha 1 (VIII) type collagens. Defects in this gene are associated with Fuchs endothelial corneal dystrophy and posterior polymorphous corneal dystrophy type 2.
Gene ID
1296
Gene Name (Vector)
collagen type VIII alpha 2 chain
Gene Symbol
COL8A2
HGNC ID
HGNC:2216
ORF Size (aa)
1284
ORF Size (bp)
1284 bp
RefSeq ID
NM_005202
RefSeq Synonyms
NM_005202, NM_001294347, BC096296,
Species
human
UniGene ID
Hs.353001
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.