human COL3A1 shRNA silencing AAV

Name
AAV-h-COL3A1-shRNA

Cat No
shAAV-205704

Availability
6-8 weeks

This is an AAV expressing shRNA for silencing of Human COL3A1.

shAAV-205704

AAV-h-COL3A1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human COL3A1 (collagen type III alpha 1 chain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

EDS4A

Description (Vector)

COL3A1 encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. (provided by R. Dalgleish, Feb 2008)

Gene ID

1281

Gene Name (Vector)

collagen type III alpha 1 chain

Gene Symbol

COL3A1

HGNC ID

HGNC:2201

ORF Size (aa)

3492

ORF Size (bp)

3492 bp

RefSeq ID

NM_000090

RefSeq Synonyms

NM_000090, BC028178,

Species

human

UniGene ID

Hs.708235

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.