human DCXR Over-expression AAV

Name
AAV-h-DCXR

Cat No
AAV-206689

Availability
4-5 weeks

This is an AAV expressing Human DCXR.

AAV-206689

AAV-h-DCXR

Ready-to-use AAV expressing Human DCXR (dicarbonyl and L-xylulose reductase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

DCR; HCR2; HCRII; KIDCR; P34H; PNTSU; SDR20C1; XR

Description (Vector)

DCXR acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.

Gene ID

51181

Gene Name (Vector)

dicarbonyl and L-xylulose reductase

Gene Symbol

DCXR

HGNC ID

HGNC:18985

ORF Size (aa)

735

ORF Size (bp)

735 bp

RefSeq ID

NM_016286

RefSeq Synonyms

NM_016286, NM_001195218, BC001470,

Species

human

UniGene ID

Hs.9857

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.