human CNTNAP1 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CNTNAP1.
shAAV-205650
AAV-h-CNTNAP1-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CNTNAP1 (contactin associated protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CASPR; CNTNAP; NRXN4; P190
Description (Vector)
The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.
Gene ID
8506
Gene Name (Vector)
contactin associated protein 1
Gene Symbol
CNTNAP1
HGNC ID
HGNC:8011
ORF Size (aa)
4155
ORF Size (bp)
4155 bp
RefSeq ID
NM_003632
RefSeq Synonyms
NM_003632, BC160132,
Species
human
UniGene ID
Hs.408730
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.