human CNPY2 shRNA silencing AAV

Name 
AAV-h-CNPY2-shRNA
Cat No 
shAAV-205621
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CNPY2.

shAAV-205621
AAV-h-CNPY2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CNPY2 (canopy FGF signaling regulator 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HP10390; MIR-interacting saposin-like protein; MSAP; protein canopy homolog 2; putative secreted protein Zsig9; TMEM4; transmembrane protein 4; ZSIG9
Description (eCommerce)
CNPY2 is a positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y2B0].
Gene ID
10330
Gene Name (eCommerce)
canopy FGF signaling regulator 2
Gene Name (Vector)
canopy FGF signaling regulator 2
Gene Symbol
CNPY2
HGNC ID
HGNC:13529
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
549
ORF Size (bp)
549 bp
Protein Name (eCommerce)
Protein canopy homolog 2
RefSeq ID
NM_014255
RefSeq Synonyms
NM_014255, NM_001190991, BC065015,
Research Areas
Gene Expression,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
CNPY2 is a positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y2B0].
UniGene ID
Hs.8752
UniProt ID (eCommerce)
Q9Y2B0

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.