human CLK2 shRNA silencing AAV

Name 
AAV-h-CLK2-shRNA
Cat No 
shAAV-205468
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CLK2.

shAAV-205468
AAV-h-CLK2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLK2 (CDC like kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
CLK2 encodes a member of the CLK family of dual specificity protein kinases. CLK family members have been shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. Note that this gene is distinct from TELO2 gene (GeneID:9894), which shares CLK2 and hCLK2 symbol aliases in common with this gene, but encodes a protein that is involved in telomere length regulation.
Gene ID
1196
Gene Name (Vector)
CDC like kinase 2
Gene Symbol
CLK2
HGNC ID
HGNC:2069
ORF Size (aa)
1500
ORF Size (bp)
1500 bp
RefSeq ID
NM_003993
RefSeq Synonyms
NM_003993, NM_001294339, NM_001294338, BC053603, BC014067,
Species
human
UniGene ID
Hs.73986

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.