human CLDN23 shRNA silencing AAV

Name 
AAV-h-CLDN23-shRNA
Cat No 
shAAV-205380
Availability
6-8 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CLDN23.

shAAV-205380
AAV-h-CLDN23-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLDN23 (claudin 23). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CLDNL; hCG1646163
Description (Vector)
CLDN23 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. CLDN23 is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. CLDN23 is down-regulated in intestinal type gastric cancer.
Gene ID
137075
Gene Name (Vector)
claudin 23
Gene Symbol
CLDN23
HGNC ID
HGNC:17591
ORF Size (aa)
879
ORF Size (bp)
879 bp
RefSeq ID
NM_194284
RefSeq Synonyms
NM_194284, BC125149, BC125148,
Species
human
UniGene ID
Hs.183617

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.