human CLASP1 shRNA silencing AAV

Name
AAV-h-CLASP1-shRNA

Cat No
shAAV-205331

Availability
4-5 weeks

This is an AAV expressing shRNA for silencing of Human CLASP1.

shAAV-205331

AAV-h-CLASP1-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CLASP1 (cytoplasmic linker associated protein 1). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

CLIP-associating protein 1; Cytoplasmic linker-associated protein 1; hOrbit1; MAST1; multiple asters 1; multiple asters homolog 1; protein Orbit homolog 1

Description (eCommerce)

CLASP1 (cytoplasmic linker-associated protein 1) localizes to the kinetochore where it regulates spindle microtubule dynamics and is required for proper chromosome alignment and segregation.

Description (Vector)

CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle (Maiato et al., 2003 (PubMed 12837247)).(supplied by OMIM, Mar 2008)

Gene ID

23332

Gene Name (eCommerce)

cytoplasmic linker associated protein 1

Gene Name (Vector)

cytoplasmic linker associated protein 1

Gene Symbol

CLASP1

HGNC ID

HGNC:17088

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

4416

ORF Size (bp)

4416 bp

Protein Name (eCommerce)

CLIP-associating protein 1

RefSeq ID

NM_015282

RefSeq Synonyms

NM_015282, NM_001207051, NM_001142274, NM_001142273, BC144107, BC132723, BC112940, BC032563,

Research Areas

Axon Guidance,Cell Cycle,Cell Division,Cytoskeleton,Golgi Apparatus,Neurobiology

Research Areas (Faceted)

cell_biology,cell_cycle,genetics,neurobiology

Species

human

Target Sentence

CLASP1 (cytoplasmic linker-associated protein 1) localizes to the kinetochore where it regulates spindle microtubule dynamics and is required for proper chromosome alignment and segregation.

UniGene ID

Hs.708183

UniProt ID (eCommerce)

Q7Z460

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.