human CIDEA shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human CIDEA.
shAAV-205280
AAV-h-CIDEA-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human CIDEA (cell death-inducing DFFA-like effector a). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CIDE-A
Description (Vector)
CIDEA encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Gene ID
1149
Gene Name (Vector)
cell death-inducing DFFA-like effector a
Gene Symbol
CIDEA
HGNC ID
HGNC:1976
ORF Size (aa)
762
ORF Size (bp)
762 bp
RefSeq ID
NM_001279
RefSeq Synonyms
NM_001318383, NM_001279, BC031896,
Species
human
UniGene ID
Hs.249129
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.