Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human CHTF8 shRNA silencing AAV

Name 
AAV-h-CHTF8-shRNA
Cat No 
shAAV-205261
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human CHTF8.

shAAV-205261
AAV-h-CHTF8-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human CHTF8 (chromosome transmission fidelity factor 8). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
62
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CTF8; DERPC
Description (Vector)
CHTF8 encodes a short protein that forms part of the Ctf18 replication factor C (RFC) complex that occurs in both yeast and mammals. The heteroheptameric RFC complex plays a role in sister chromatid cohesion and may load the replication clamp PCNA (proliferating cell nuclear antigen) onto DNA during DNA replication and repair. CHTF8 is ubiquitously expressed and has been shown to have reduced expression in renal and prostate tumors. Alternatively spliced transcript variants have been described. CHTF8 has a pseudogene on chromosome X.
Gene ID
54921
Gene Name (Vector)
chromosome transmission fidelity factor 8
Gene Symbol
CHTF8
HGNC ID
HGNC:24353
ORF Size (aa)
366
RefSeq ID
NM_001040146
RefSeq Synonyms
NM_001040146, NM_001039690, BC018700,
Species
human
UniGene ID
Hs.85962

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.